Wiedmann, Martin
Associate Professor
The overall goal of Martin?s academic program is to develop and communicate the scientific knowledge needed to prevent and control foodborne and zoonotic diseases caused by bacteria. Current work in my laboratory focuses on microorganisms that cause a considerable number of foodborne deaths annually in the US, including Listeria monocytogenes and Salmonella. Listeria monocytogenes causes disease in more than 20 animal species as well as a severe, but rare human foodborne disease with about 500 human deaths annually in the US alone. Salmonella also causes disease in many animals as well as a common foodborne disease in humans with approximately 1.4 million cases and 550 deaths annually in the US. With his training as a both a veterinarian and food scientist, Martin?s programs focus on a comprehensive and interdisciplinary farm-to-table approach to food safety. Martin?s academic programs thus involves the application of a variety of disciplines (including microbiology and microbial genetics, population genetics, molecular biology, genomics, evolution and modelling) as well as collaborators from many different discipline (e.g., economics, computer science, veterinary medicine, epidemiology and statistics) and from many different institutions (other universities, state health and agriculture departments, federal agencies such as CDC and USDA, as well as trade organizations).
research
research and scholarship focus
The specific objective of my research program is to develop a better understanding of the pathogenesis, ecology, evolution, and transmission of bacterial foodborne and zoonotic diseases. The pathogenesis of foodborne and zoonotic diseases can involve complex interactions between a bacterial pathogen, a variety of environments and one or multiple host species. The ability of bacterial cells to survive and compete in a variety of environments plays a key role in the pathogenesis and transmission of many foodborne diseases. In addition, selective pressures not associated with mammalian hosts may contribute significantly to the emergence and evolution of virulence characteristics related to the ability of bacteria to effectively infect mammalian hosts. Foodborne zoonotic pathogens provide ideal model systems for studying the ecology of infectious diseases, including adaptation of clonal groups to specific hosts and non-host environments as well as virulence gene expression and maintenance of virulence characteristics under widely varying conditions, including those not directly associated with a host. Current work in my laboratory focuses on two model organisms, Listeria monocytogenes and Salmonella.
primary investigator of
- APPLICATION AND DEVELOPMENT OF THE PATHOGEN TRACKER DATABASE FOR PHENOTYPIC AND SUBTYPING STUDIES OF L. MONOCYTOGENES AND SALMONELLA | Research Grant
- DEVELOPMENT AND IMPLEMENTATION OF GENOMICS-BASED APPROACHES FOR MOLECULAR SUBTYPING AND SEROTYPING OF L. MONOCYTOGENES, AND SALMONELLA | Research Grant
- IDENTIFICATION AND CHARACTERIZATION OF VIRULENCE ATTENUATED L. MONOCYTOGENES WITH UNIQUE MUTATION IN INTERNALIN A | Research Grant
- INTEGRATION OF TEACHING, RESEARCH, AND OUTREACH EFFORTS TO FACILITATE INDUSTRY APPLICATION OF MOLECULAR SUBTYPING METHODS FOR FOODBORNE PATHOGENS | Research Grant
- LISTERIA MONOCYGTOGENES SAMPLES: ILSI NORTH AMERICA LISTERIA MONOCYTOGENES AND ENTEROBACTER SAKAZAKII REFERENCE STRAIN COLLECTION | Research Grant
- TRACKING AND UNDERSTANDING FOODBORNE TRANSMISSION OF L. MONOCYTOGENES, E. COLI, AND SALMONELLA USING GENOMICS AND MOLECULAR APPROACHES | Research Grant
- UNDERSTANDING AND CONTROLLING MONOCYTOGENES TRANSMISSION THROUGH READY-TO-EAT MEAT PRODUCTS FROM PROCESSING PLANT TO CONSUMER | Research Grant
- USE OF AUTOMATED RIBOTYPING IN BIOFORENSICS FOR MOLECULAR SUBTYPING OF BIOLOGICAL AGENTS | Research Grant
co investigator of
- FOOD SCIENCE MULTICULTURAL SCHOLARS PROGRAM | Research Grant
- LISTERIA MONOCYTOGENES STRESS RESPONSE SYSTEMS AND THEIR SIGNIFICANCE FOR SURVIVAL IN FOOD PROCESSING ENVIRONMENTS | Research Grant
- MINIMIZING MICROBIAL FOOD SAFETY HAZARDS OF FRESH AND FRESH-CUT FRUITS AND VEGETABLES THROUGH A FARM TO TABLE APPROACH | Research Grant
- PH.D. TRAINING IN FARM-TO-TABLE FOOD SAFETY AND BIOSECURITY | Research Grant
- RAPID IMMUNOASSAY SILVER AMPLIFICATION TEST SYSTEM | Research Grant
- REGULATORY NETWORKS CONTRIBUTING TO L. MONOCYTOGENES TRANSMISSION AND VIRULENCE | Research Grant
research areas
- applied economics | collaborative research area (CALS)
- bioinformatics | collaborative research area (CALS)
- biomedical sciences | collaborative research area (CALS)
- computational biology | research concentration area (Engineering)
- dairy science | collaborative research area (CALS)
- evolution | collaborative research area (CALS)
- food science | collaborative research area (CALS)
- genomics | collaborative research area (CALS)
- microbiology | collaborative research area (CALS)
- molecular biology | collaborative research area (CALS)
- new life sciences | collaborative research area (CALS)
- pathogens | collaborative research area (CALS)
- veterinary medicine | collaborative research area (CALS)
submitted impact statement
- Training the next generation of food scientists: The food science undergraduate summer research program | 2007 Impact statement
- Food Science Research opportunities for Undergraduates | 2005 Impact statement
- Understanding farm-to-table Listeria monocytogenes transmission in order to reduce food-borne disease in humans. | 2004 Impact statement
- Food science research opportunities for undergraduates | 2004 Impact statement
affiliations
head of
- Laboratory for Molecular Typing | laboratory service facility
- Microbial Genomics | NLSI/Genomics focus area
- Pathogen Tracker project | research project
faculty appointment in
- Food Science (FOOD) | Cornell department
member of graduate field
- Comparative Biomedical Sciences | graduate field
- Food Science and Technology | graduate field
- Microbiology | graduate field
other Cornell affiliations
- Cornell Center for Comparative and Population Genomics | research and educational resource center
- Infectious Diseases and Biodefence Committee | committee
- Northeast Dairy Foods Research Center | extension program unit
administrative responsibilities
Director of Graduate Studies
member of advisory group
- Life Sciences Core Laboratories Center DNA Sequencing Faculty Advisory Group | advisory committee
teaching
teaching focus
My teaching program focuses on helping students to not only better understand subject areas, but more importantly to help them acquire and improve their critical thinking and life-long learning skills. My class room teaching thus tries to increasingly include case-based learning strategies. I also have a strong commitment to providing undergraduate research opportunities, since I see undergraduate research as an outstanding way to teach critical thinking and independent learning skills. The specific subject matter objective of my teaching program focuses on communicating (i) the knowledge needed to assure a safe food supply from farm-to-table and (ii) the general role of microorganisms in food production and processing. Courses taught include FD SCI 351 (Milk Quality), FD SCI 406 (Food and Dairy Fermentations), FD SCI 607 (Advanced Food Microbiology), FD SCI 695 (Current Readings in Food Science (FOOD 695), VTMED 741 (Microbial safety of animal-based foods).
teaches
- FDSC 4060 - Dairy and Food Fermentations (R 12:20:PM-02:15:PM) | fall 2009 class
- FDSC 4960 - Undergraduate Internship in Food Science (TBA -) | fall 2009 class
- FDSC 4970 - Individual Study in Food Science (TBA -) | fall 2009 class
- FDSC 4980 - Undergraduate Teaching Experience (TBA -) | fall 2009 class
- FDSC 4990 - Undergraduate Research in Food Science (TBA -) | fall 2009 class
- FDSC 5000 - Master of Professional Studies (Agriculture) Project (TBA -) | fall 2009 class
- FDSC 6940 - Special Topics in Food Science (R 02:30:PM-04:25:PM) | fall 2009 class
- FDSC 6950 - Current Readings in Food Science (TBA -) | fall 2009 class
- FDSC 6960 - Graduate Internship in Food Science (TBA -) | fall 2009 class
- FDSC 6980 - Graduate Teaching Experience (TBA -) | fall 2009 class
- FDSC 8900 - Masters-Level Thesis Research (TBA -) | fall 2009 class
- FDSC 9900 - Doctoral-Level Thesis Research (TBA -) | fall 2009 class
- FDSC 4960 - Undergraduate Internship in Food Science (TBA -) | spring 2009 class
- FDSC 4970 - Individual Study in Food Science (TBA -) | spring 2009 class
- FDSC 4980 - Undergraduate Teaching Experience (TBA -) | spring 2009 class
- FDSC 5000 - Master of Professional Studies (Agriculture) Project (TBA -) | spring 2009 class
- FDSC 8900 - Masters-Level Thesis Research (TBA -) | spring 2009 class
- FDSC 9900 - Doctoral-Level Thesis Research (TBA -) | spring 2009 class
- FDSC 3510 - Milk Quality (F 12:20:PM-01:10:PM) | fall 2008 class
- FDSC 4060 - Dairy and Food Fermentations (R 12:20:PM-02:15:PM) | fall 2008 class
- FDSC 6940 - Special Topics in Food Science (R 02:30:PM-04:25:PM) | fall 2008 class
service
outreach focus
Extension and outreach efforts focus on working with industry partners (producers and farmers, food processors, retailers), trade organizations (e.g., American Meat Institute, Food Marketing Institute, Food Products Association, National Fisheries Institute), as well as federal and state agencies to design and conduct applied field research studies as well as to conduct workshops and training programs aimed at controlling foodborne pathogen transmission. Work conducted to date and in progress includes field studies on L. monocytogenes transmission in dairy, meat, and seafood processing plants, retail operations, and on farms as well as studies on Salmonella transmission on farms. Extensive workshop series on Listeria control in processing plants are also being conducted; current efforts are increasingly focusing on developing and delivering training programs for Listeria control at the retail level.
current professional activities
- Editorial Board of the American Journal of Veterinary research (1999-2001)
- Editorial Board of the Journal of Food Protection ( present )
- Editorial Board of Applied and Environmental Microbiology ( present )
- Member of the Graduate Fields of Food Science, Microbiology, and Comparative Biomedical Sciences, Cornell
background
educational background
- Veterinary Degree (DVM equivalent), University of Munich, Germany, 1992
- Dr. Med. Vet. (Ph.D. equivalent), University of Munich, Germany, 1994
- Ph.D., Food Science, Cornell University, 1997
professional background
- Cornell faculty, since 1999
- Co-coordinator, Cornell Food and Water Safety Program
- Participates in the Infection and Pathobiology Program and in the Cornell Genomics Initiative
- Director of the Cornell Institute of Food Science Summer Scholar Program, Cornell
- Director of the Cornell Laboratory of Molecular Typing
featured in
- Cornell food scientists awarded $1.67 million to improve fresh food safety | Cornell Chronicle feature
- Cornell partners with Indian university to offer innovative degree in food science | Cornell Chronicle feature
- Cornell researcher helps lead $2 million project to prevent Listeria contamination in ready-to-eat foods | Cornell Chronicle feature
- CU food scientists keep watch over New York dairy foods | Cornell Chronicle feature
- With $1.1 million from Sea Grant, Cornell to study PCBs, lake invaders and more | Cornell Chronicle feature
publications
linked articles
- Alternative sigma factor sigmaB is not essential for listeria monocytogenes surface attachment. | journal article
- Associations among Listeria monocytogenes genotypes and distinct clinical manifestations of listeriosis in cattle | journal article
- Contributions of Listeria monocytogenes sigma(B) and PrfA to expression of virulence and stress response genes during extra- and intracellular growth | journal article
- Daily variability of Listeria contamination patterns in a cold-smoked salmon processing operation | journal article
- Genetic and phenotypic characterization of Listeria monocytogenes lineage III | journal article
- Listeria monocytogenes internalins are highly diverse and evolved by recombination and positive selection | journal article
- Longitudinal studies on Listeria in smoked fish plants: Impact of intervention strategies on contamination patterns | journal article
- Low prevalence of Listeria monocytogenes in human stool. | journal article
- Mathematical model of Listeria monocytogenes cross-contamination in a fish processing plant | journal article
- Molecular epidemiology and cluster analysis of human listeriosis cases in three US States | journal article
- sigmaB-dependent gene induction and expression in Listeria monocytogenes during osmotic and acid stress conditions simulating the intestinal environment | journal article
Keywords: food microbiology, food safety, food science, genomics, infectious disease, infectious diseases, listeria monocytogenes, microbiology, molecular microbiology, salmonella, zoonotic diseases