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• A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolism
• A genetic and structural analysis of the yeast Vps15 protein kinase: Evidence for a direct role of Vps15p in vacuolar protein delivery
• A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole
• A molecular switch required for retrovirus assembly participates in the hexagonal immature lattice.
• A phosphotyrosine displacement mechanism for activation of Src by PTPα
• A role for coactivators and histone acetylation in estrogen receptor α-mediated transcription initiation
• Accumulation of mitochondrially synthesized Saccharomyces cerevisiae Cox2p and Cox3p depends on targeting information in untranslated portions of their mRNAs
• Activation of Src and transformation by a RPTPα splice mutant found in human tumors
• At least two nuclear gene products are specifically required for translation of a single yeast mitochondrial mRNA
• Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway
• Characterization of The virA Locus of Agrobacterium tumefaciens: a transcriptional regulator and host range determinant
• Chromatin exposes intrinsic differences in the transcriptional activities of ER and ER
• Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function
• Cytoplasm to vacuole trafficking of Aminopeptidase I requires t-SNARE/Sec1p complex composed of Tlg2p and Vps45p
• DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1.
• Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer
• Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription
• ESCRT-II coordinates the assembly of ESCRT-III finalments required for cargo sorting and multivesicular body vesicle formation
• Embryonic expression of the period gene in the central nervous system of Drosophila melanogaster
• Endosome transport function in yeast requires novel AAA-type ATPase, Vps4p
• Genome-wide Lethality Screen Identifies New PI4,5P2 Effectors that regulat the Actin Cytoskeleton
• Heat shock proteins can substi¬tute for SecB function during protein export in Escherichia coli
• Interactions of ribosome nascent chain complexes of the chloroplast-encoded D1 thylakoid membrane protein with cpSRP54
• Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 oncoprotein to a select interaction with the candidate tumor suppressor protein ZO-2
• Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes.
• Maize streak virus genes essential for systemic spread and symptom development.
• Membrane protein sorting: Biosynthesis, transport, and processing of yeast vacuolar alkaline phosphatase
• Mss51p promotes mitochondrial Cox1p synthesis and interacts with newly synthesized Cox1p
• Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component
• Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities
• Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter
• Quantitative Proliferation Dynamics and Random Chromosome Segregation of Hair Follicle Stem Cells
• Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase
• SMG 5, required for nonsense mediated mRNA decay, associates with SMG 2 and protein phosphatase 2A
• Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription
• Spatial and temporal pattern of hsp26 expression during normal development
• Structural insight into the ESCRT-I/-II super-complex and its interaction networks on membranes
• Structure of a trapped endonuclease III-DNA covalent intermediate
• Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer
• Targeted genetic inactivation of the photosystem I reaction center in the cyanobacterium Synechocystis sp. PCC 6803
• The Drosophila BRM complex facilitates global transcription by RNA polymerase II
• The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function
• The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P2 synthesis at the plasma membrane.
• The exomer cargo adaptor structure reveals a novel GTPase-binding domain.
• The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
• The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has the properties of a membrane cytoskeletal linker in the induced apical microvilli
• The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA target
• Two group I ribozymes with different functions in a nuclear rDNA intron
• Two mechanisms activate PTPα during mitosis
• Ubiquitin interactions of NZF zinc fingers
• Ubiquitinated Cargo is Essential for the ESCRT-dependent Formation of Multivesicular Body Intralumenal Vesicals
• VPS21 encodes a rab5-like GTP-binding protein required for the sorting of yeast vacuolar proteins
• Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin, and are required for endocytosis
• cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1