- Fluorescence microscopy is a powerful tool for cell biology and biochemistry. It can provide information about subsets of cells and about structures, molecules and proteins within cells. In the past, the potential of this technique for providing the drug screener with this same wealth of information was limited by the inability to automate the process. Recent advances in instrumentation and software now make automated fluorescence imaging a practical tool in screening and drug discovery. Investigators at Weill Medical College now have access to this powerful research tool.