co-principal investigator on ROLE OF MICROVASCULAR LESIONS IN ALZHEIMER'S DISEASE awarded by NATL INST OF HEALTH DHHS 2012 - 2013
individual publications academic article A practical guide to measurement and manipulation of blood flow at the level of single microvessels in rodent cortex. Journal of Cerebral Blood Flow and Metabolism. 32:1277. 2012 In Vivo Two-photon Excited Fluorescence Microscopy Reveals Cardiac- and Respiration-Dependent Pulsatile Blood Flow in Cortical Blood Vessels in Mice. American Journal of Physiology. 2012 In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile flow in cortical blood vessels in mice. American Journal of Physiology, Heart and Circulatory Physiology. 32. 2012 Age-related intimal stiffening promotes atherosclerosis by enhancing endothelial permeability and leukocyte transmigration. Science Translational Medicine. 3. 2011 Cortical microhemorrhages cause local inflammation but do not trigger dendrite pathology. PLOS One. 6. 2011 Real-time imaging of perivascular transport of nanoparticles during convection enhanced delivery in the rat cortex. Annals of Biomedical Engineering. 40. 2011 Limitations of collateral flow after occlusion of a single cortical penetrating arteriole. Journal of Cerebral Blood Flow and Metabolism. 30. 2010 Penetrating arterioles: A bottleneck in the perfusion of cortex. Proceeding of the National Academy of Science. 104. 2007 Targeted insult to individual subsurface cortical blood vessels using ultrashort laser pulses: Three models of stroke. Nature Methods. 3. 2006
teaching activities BME-4110: Science and Technology Approaches to Problems in Human Health - Fall 2012