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Shuler, Michael Louis
James M. and Marsha McCormick Chair of Biomedical Engineering, Samuel B. Eckert Professor of Chemical Engineering
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- Professor, Biomedical Engineering (BME), College of Engineering
- Department Chairperson, Biomedical Engineering (BME), College of Engineering
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Affiliations
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other Cornell affiliations
Research
principal investigator on
- CENTER ON THE MICROENVIRONMENT AND METASTASIS awarded by NATL CANCER INSTITUTE, NIH 2009 - 2014
- COLLABORATIVE CURRICULUM DEVELOPMENT: INTERDISCIPLINARY MIDDLE AND HIGH SCHOOL EDUCATION IN BIOMEDICAL ENGINEERING THROUGH GRADUATE STUDENT/TEACHER INTERACTION PROGRAM awarded by NATL SCIENCE FOUNDATION 2009 - 2014
- MICROFABRICATED IN VITRO MODEL OF A LUNG awarded by US ARMY 2010 - 2012
- MICROPHYSIOLOGICAL SYSTEMS ADN LOW COST MICROFLUIDIC PLATFORM WITH ANALYTICS awarded by NATL INST OF NEUR DIS & STROKE, NIH 2012 - 2014
- TARGETING CANCER STEM CELL SELF-RENEWAL AND PROLIFERATION MECHANISMS USING IN VITRO MICROSCALE MODELS awarded by NATL SCIENCE FOUNDATION 2011 - 2014
Publications
individual publications
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academic article
- Development of Disposable PDMS Micro Cell Culture Analog Devices with Photopolymerizable Hydrogel Encapsulating Living Cells. Biomedical Microdevices. 14:409-418. 2012
- Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor. Biotechnology and Bioengineering. 109:137-145. 2012
- On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’ devices. Biomedical Microdevices. 14:895-906. 2012
- An uncertain role for Cu(II) in stimulating Mn oxidation by Leptothrix discophora SS-1. Archives of Microbiology. 193 :89. 2011
- An uncertain role for Cu(II) in stimulating Mn oxidation by Leptothrix discophora SS-1. Archives of Microbiology. 193 :89. 2011
- Microscale 3-D hydrogel scaffold for biomimetic gastrointestingal (GI) tract model.. Lab on a Chip. 11:389-392. 2011
- Murine in vitro model of the blood brain barrier for evaluating drug transport.. European Journal of Pharmacology. 42:148-155. 2011
- A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip. Lab on a Chip. 10:446-55. 2010
- Considerations for the design and construction of a synthetic platform cell for biotechnological applications. Biotechnology and Bioengineering. 105:26-36. 2010
- Considerations for the design and construction of a synthetic platform cell for biotechnological applications.. Biotechnology and Bioengineering. 105:26-36. 2010
- In vitro microscale systems for systematic drug toxicity study. Bioprocess Biosyst Eng. 33:5-19. 2010
- Integration of in silico and in vitro platforms for pharmacokinetic–modeling.. Expert Opinion On Drug Metabolism andToxicology. 6:1-19. 2010
- Investigation of portable in situ fluorescence optical detection for microfluidic 3D cell culture assays.. Optics Letters. 35:1374-1376. 2010
- A combined pharmacokinetic-pharmacodynamic (PK-PD) model for tumor growth in the rat with UFT administration. J Pharm Sci. 98:1885-904. 2009
- A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs. Lab on a Chip. 9:1385-94. 2009
- A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers. Biotechnology and Bioengineering. 103:187-98. 2009
- Cell Cycle Progression in Escherichia coli B/r Affects Transcription of Certain Genes: Implications for Synthetic Genome Design. Biotechnology and Bioengineering. 102:902-909. 2009
- Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability. J Nutr Biochem. 20:494-502. 2009
- Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity. Biotechnology and Bioengineering. 104:193-205. 2009
- Detection of Avian Influenza-DNA Hybridization Using Wavelength-scanning Surface Plasmon Resonance Biosensor. Journal of the Optical Society of Korea. 13:392-397. 2009
- Effect of iron concentration on the growth rate of Pseudomonas syringae and the expression of virulence factors in hrp-inducing minimal medium. Appl Environ Microbiol. 75:2720-6. 2009
- Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices. Biotechnology and Bioengineering. 104:516-25. 2009
- Iron requirement for Mn (II) oxidation by Leptothrix discophora SS-1. . Applied and Environmental Microbiology. 75:1229-1235. 2009
- Prevention of air bubble formation in a microfluidic perfusion cell culture system using a microscale bubble trap. Biomedical Microdevices. 11:731-8. 2009
- Accelerating innovation between surgeons and biomedical engineers in the academic setting. Surgery. 143:171-175. 2008
- An actively mixed mini-bioreactor for protein production from suspended animal cells. Biotechnology and Bioengineering. 100:72-81. 2008
- Biomedical Technologies for In Vitro Screening and Controlled Delivery of Neuroactive Compounds. Central Nervous System Agents in Medicinal Chemistry. 8:203-219. 2008
- Development of a Gastrointestinal Tract Microscale Cell Culture Analog to Predict Drug Transport. MCB. 5:119-132. 2008
- Development of a Stable Dual Cell-Line GFP Expression System to Study Estrogenic Endocrine Disruptors. Biotechnol. Bioeng.. 101:1276-1287. 2008
- Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors. Biotechnology and Bioengineering. 101:1276-1287. 2008
- Engineered bacterial outer membrane vesicles with enhanced functionality. J. Mol. Biol.. 380:51-66. 2008
- Engineered bacterial outer membrane vesicles with enhanced functionality. Journal of Molecular Biology. 380:51-66. 2008
- Fabrication of a multiple-diameter branched network of microvascular channels with semi-circular cross-sections using xenon difluoride etching. Biomedical Microdevices. 10:179-186. 2008
- Incorporating genome-wide DNA sequence information into a dynamic whole-cell model of Escherichia coli: application to DNA replication. IET Syst. Biol.. 2:369-382. 2008
- Incorporating genome-wide DNA sequence information into a dynamic whole-cell model of Escherichia coli: application to DNA replication. IET Systems Biology. 2:369-382. 2008
- Optical measurement of neural activity using surface plasmon resonance. Optics Letters. 33:914-916. 2008
- Optical measurement of neural activity using surface plasmon resonance. Optics Letters. 33:914-916. 2008
- Sensitivity enhancement of surface plasmon resonance imaging using periodic metallic nanowires. Journal of Lightwave Technology. 26:1472-1478. 2008
- A genomically/chemically complete module for synthesis of lipid membrane in a minimal cell. Biotechnology and Bioengineering. 97:397-409. 2007
- A hydrogel-based microfluidic device for the studies of directed cell migration. Lab on a Chip. 7:763-769. 2007
- Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus. Biotechnology Letters. 29:237-246. 2007
- Influence of culture medium supplementation of tobacco NT1 cell suspension cultures on the N-glycosylation of human secreted alkaline phosphatase. Biotechnology and Bioengineering. 97:1585-1593. 2007
- Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis. Biotechnology and Bioengineering. 98:318-327. 2007
- Real-time fluorescence detection of multiple microscale cell culture analog devices In situ. Cytometry Part A. 71A:857-865. 2007
- Sensitivity and control analysis of periodically forced reaction networks using the Green's function method. Journal of Theoretical Biology. 247:442-461. 2007
- Spatial distributions of copper in microbial biofilms by scanning electrochemical microscopy. Environmental Science & Technology. 41:936-941. 2007
- Three-dimensional hydrogel cultures for modeling changes in tissue impedance around microfabricated neural probes. Journal of Neural Engineering. 4:399-409. 2007
- A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis. Lab on a Chip. 6:381-388. 2006
- A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis. Lab on a Chip. 6:381-388. 2006
- Antibody-based surface plasmon resonance detection of intact viral pathogen. Biotechnology and Bioengineering. 94:815-819. 2006
- Application of Mucin and Caco-2/goblet Cell Co-cultures to Refine the in vitro Digestion/Caco-2 Cell Model for Iron Uptake . Experimental Biology. 2006
- Cycling of biogenic Mn-oxides in a model microbial predator-prey system. Geomicrobiology Journal. 23:37-43. 2006
- Design optimization of nano-grating surface plasmon resonance sensors. Optics Express. 14:4842-4849. 2006
- Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures. Biotechnology and Bioengineering. 95:8-14. 2006
- Evaluation of Mut(+) and Mut(S) Pichia pastoris phenotypes for high level extracellular scFv expression under feedback control of the methanol concentration. Biotechnology Progress. 22:881-888. 2006
- Evaluation of Mut+ and MutS Pichia pastoris phenotypes for high level extracellular scFv expression under feedback control of the methanol concentration. Biotechnology Progress. 22:881-888. 2006
- Production, secretion, and stability of human secreted alkaline phosphatase in tobacco NT1 cell suspension cultures. Biotechnology Progress. 22:1643-1649. 2006
- An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane. Lab on a Chip. 5:74-85. 2005
- Behavior of lead in a model microbial predator-prey system. Environmental Toxicology and Chemistry. 24:2734-2741. 2005
- Cycling of Biogenic Mn-oxides in a Model Microbial Predator-Prey System. Geomicrobiology Journal. 23:37-43. 2005
- Determination of spatial distributions of zinc and active biomass in microbial biofilms by two-photon laser scanning microscopy. Applied Environmental Microbiology. 71:4014-4021. 2005
- Development of a microscale cell culture analog device to probe naphthalene toxicity.. Abstracts of Papers of the American Chemical Society. 229. 2005
- Exploring biofilms with two-photon laser scanning microscopy.. Abstracts of Papers of the American Chemical Society. 229. 2005
- Expression of human secreted alkaline phosphatase (SEAP) in tobacco NT1 cell suspension cultures and kinetic studies of protein accumulation and stability in the extracellular medium.. Abstracts of Papers of the American Chemical Society. 229. 2005
- Portable in situ fluorescence cytometry of microscale cell-based assays. Optics Letters. 30:1689-1691. 2005
- Relationship of viability and apoptosis to taxol production in Taxus sp. suspension cultures elicited with methyl jasmonate. Biotechnol Prog. 21:700-7. 2005
- Sparge gas composition affects biomass and ajmalicine production from immobilized cell cultures of Catharanthus roseus. Enzyme and Microbial Technology. 37:424-434. 2005
- The behavior of lead in a model microbial predator-prey system. Environmental Toxicology and Chemistry. 24:2734-2741. 2005
- A modular minimal cell model: Purine and pyrimidine transport and metabolism. PNAS. 101:6681-6686. 2004
- A self-priming microfluidic diaphragm pump capable of recirculation fabricated by combining soft lithography and traditional machining. Biotechnology and Bioengineering. 85:359-363. 2004
- Development of a microscale cell culture analog to probe naphthalene toxicity. Biotechnology Progress. 20:316-323. 2004
- Development of a model microbial predator-prey system suitable for studies of the behavior of toxic trace metals. Environmental Toxicology and Chemistry. 23:292-297. 2004
- Effect of subculture and elicitation on instability of taxol production in Taxus sp. suspension cultures. Biotechnol Prog. 20:1666-73. 2004
- Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines. Biotechnology Progress. 20:1273-1279. 2004
- Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines. Biotechnology Progress. 20:1273-1279. 2004
- Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies. Biotechnology Progress. 20:590-597. 2004
- Lipid-gel and poly(dimethylsiloxane) film to mimic bioaccumulation in adipocytes. Biotechnology and Bioengineering. 86:643-649. 2004
- Mobilization of adsorbed copper and lead from naturally aged soil by bacterial extracellular polymers. Water Research. 38:1121-1128. 2004
- Predicting the rate and extent of cadmium and copper desorption from soils in the presence of bacterial extracellular polymer. Water Research. 38:2231-2240. 2004
- Robust control of initiation of prokaryotic chromosome replication: Essential considerations for a minimal cell. Biotechnology and Bioengineering. 88:575-584. 2004
- The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors. Biotechnology Progress. 20:338-345. 2004
- A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Reports. 21:1217-1220. 2003
- Effect of culture conditions on the degree of sialylation of a recombinant glycoprotein expressed in insect cells. Biotechnology Progress. 19:739-749. 2003
- Effect of silkworm hemolymph on N-linked glycosylation in two Trichoplusia ni insect cell lines. Biotechnology and Bioengineering. 83:695-705. 2003
- Growth of endothelial cells on microfabricated silicon nitride membranes for an in vitro model of the blood-brain barrier. Biotechnology and Bioprocess Engineering. 8:246-251. 2003
- Integration of cell culture and microfabrication technology. Biotechnol Prog. 19:243-53. 2003
- Novel insect cell line capable of complex N-glycosylation and sialylation of recombinant proteins. Biotechnology Progress. 19:185-192. 2003
- Production of a sialylated N-linked glycoprotein in insect cells: Role of glycosidases and effect of harvest time on glycosylation. Biotechnology Progress. 19:193-201. 2003
- Production of proteins with complex glycosylation in insect cells.. Abstracts of Papers of the American Chemical Society. 225. 2003
- Structural characterization of plant-derived hepatitis B surface antigen employed in oral immunization studies. Vaccine. 21:4011-4021. 2003
- Alterations in taxol production in plant cell culture via manipulation of the phenylalanine ammonia lyase pathway. Biotechnology Progress. 18:1149-1156. 2002
- Effect of oxide formation mechanisms on lead adsorption by biogenic manganese (hydr)oxides, iron (hydr)oxides, and their mixtures. Environmental Science & Technology. 36:421-425. 2002
- Factors important in the extraction, stability and in vitro assembly of the hepatitis B surface antigen derived from recombinant plant systems. Biotechnology Progress. 18:538-550. 2002
- Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form. Biotechnology and Bioengineering. 80:812-822. 2002
- Kinetics of Mn(II) oxidation by Leptothrix discophora SS1. Geochimica Et Cosmochimica Acta. 66:773-781. 2002
- Prediction of naphthalene bioaccumulation using an adipocyte cell line model. Biotechnology Progress. 18:174-181. 2002
- The effect of ajmalicine spiking and resin addition timing on the production of indole alkaloids from Catharanthus roseus cell cultures. Biotechnology and Bioengineering. 79:408-415. 2002
- The effect of various substrates on cell attachment and differentiation of 3T3-F442A preadipocytes. Biotechnology and Bioengineering. 78:454-458. 2002
- Use of medium additives to improve glycosylation in a Trichoplusia NI insect cell line.. Abstracts of Papers of the American Chemical Society. 224. 2002
- Adsorption properties of mixed ferric and biogenic manganese oxides.. Abstracts of Papers of the American Chemical Society. 221. 2001
- Comparison of growth and recombinant protein expression in two different insect cell lines in attached and suspension culture. Biotechnology Progress. 17:676-684. 2001
- Enhanced in-situ mobilization and biodegradation of phenanthrene from soil by a solvent/surfactant system. Journal of Microbiology and Biotechnology. 11:716-719. 2001
- Kinetics of Mn oxidation by Leptothrix discophora SS1.. Abstracts of Papers of the American Chemical Society. 221. 2001
- Phenanthrene desorption from soil in the presence of bacterial extracellular polymer: Observations and model predictions of dynamic behavior. Water Research. 35:835-843. 2001
- Production of a sialylated N-linked glycoprotein in insect cells. Biotechnology Progress. 17:822-827. 2001
- The effects of pH and surface composition of Pb adsorption to natural freshwater biofilms. Environmental Science & Technology. 35:3182-3189. 2001
- Towards the development of a minimal cell model by generalization of a model of Escherichia coli: Use of dimensionless rate parameters. Biotechnology and Bioengineering. 76:187-192. 2001
- Adsorption of Pb and Cd onto metal oxides and organic material in natural surface coatings as determined by selective extractions: new evidence for the importance of Mn and Fe oxides. Water Research. 34:427-436. 2000
- Camptothecine from callus cultures of Nothapodytes foetida. Biotechnology Letters. 22:129-132. 2000
- Cell science and protein crystal growth research for the international space station. Journal of Cellular Biochemistry. 79:662-671. 2000
- Characterization of a perfusion reactor utilizing mammalian cells on microcarrier beads. Biotechnology Progress. 16:471-479. 2000
- Characterization of hepatitis B surface antigen production in plant cell tissue culture end evaluation of the system's economic feasibility.. Abstracts of Papers of the American Chemical Society. 219. 2000
- Combining cell culture analogue reactor designs and PBPK models to probe mechanisms of naphthalene toxicity. Biotechnology Progress. 16:334-345. 2000
- Computer-Model for Glucose-Limited Growth of a Single Cell of Escherichia-Coli B/R-A. Biotechnology and Bioengineering. 67:827-840. 2000
- Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein. Biotechnology Progress. 16:650-656. 2000
- Modeling the desorptive release of nonionic organic contaminants in heterogeneous soil matrices.. Abstracts of Papers of the American Chemical Society. 220. 2000
- Process options in hepatitis B surface antigen extraction from transgenic potato. Biotechnology Progress. 16:435-441. 2000
- The effect of inoculum density and conditioned medium on the production of ajmalicine and catharanthine from immobilized Catharanthus roseus cells. Biotechnology and Bioengineering. 67:61-71. 2000
- Use of amphiphilic polymer particles for in situ extraction of sorbed phenanthrene from a contaminated aquifer material. Environmental Science & Technology. 34:4133-4139. 2000
- Functional genomics: An opportunity for bioengineers. Biotechnol Prog. 15:287. 1999
- Glycobiology: Insecta can perform human-type glycosylation. Glycobiology. 9:1126-1126. 1999
- Glycosylation of a recombinant protein in the Tn5B1-4 insect cell line: Influence of ammonia, time of harvest, temperature, and dissolved oxygen. Biotechnology and Bioengineering. 63:255-262. 1999
- Independent prediction of naphthalene transport and biodegradation in soil with a mathematical model. Biotechnology and Bioengineering. 65:65-75. 1999
- Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of Taxus canadensis elicited with methyl jasmonate. Journal of Natural Products. 62:1395-1398. 1999
- Lead binding to metal oxide and organic phases of natural aquatic biofilms. Limnology and Oceanography. 44:1715-1729. 1999
- Production of biogenic Mn oxides by Leprothrix discophora SS-1 in a chemically defined growth medium and evaluation of their Pb adsorption characteristics. Applied and Environmental Microbiology. 65:175-180. 1999
- Single-cell models: promise and limitations. J Biotechnol. 71:225-8. 1999
- The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. Biotechnology and Bioengineering. 62:97-105. 1999
- The use of lectins to select subpopulations of insect cells. Biotechnology and Bioengineering. 64:616-619. 1999
- Trace metal adsorptive capacity of discreet naturally occurring surface coating phases in aquatic environments.. Abstracts of Papers of the American Chemical Society. 217. 1999
- Use of in vitro data for construction of a physiologically based pharmacokinetic model for naphthalene in rats and mice to probe species differences. Biotechnology Progress. 15:540-555. 1999
- Use of mannosamine for inducing the addition of outer arm N-acetylglucosamine onto N-linked oligosaccharides of recombinant proteins in insect cells. Biotechnology Progress. 15:168-173. 1999
- Validation of a hybrid "two-site gamma" model for naphthalene desorption kinetics. Environmental Science & Technology. 33:3241-3248. 1999
- Different in vitro systems affect CYPIA1 activity in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology in Vitro. 12:259-272. 1998
- Effects of long-term passaging of BTI-Tn5B1-4 insect cells on growth and recombinant protein production. Biotechnology Progress. 14:543-547. 1998
- Enhanced in-situ mobilization and biodegradation of phenanthrene from the soil by solvent/surfactant. Abstracts of Papers of the American Chemical Society. 216. 1998
- Growth kinetics of Pseudomonas putida G7 on naphthalene and occurrence of naphthalene toxicity during nutrient deprivation. Biotechnology and Bioengineering. 59:587-94. 1998
- Hg2+ removal by genetically engineered Escherichia coli in a hollow fiber bioreactor. Biotechnology Progress. 14:667-671. 1998
- Low-cost serum-free medium for the BTI-Tn5B1-4 insect cell line. Biotechnology Progress. 14:573-579. 1998
- N-glycosylation of a baculovirus-expressed recombinant glycoprotein in three insect cell lines. In Vitro Cellular & Developmental Biology-Animal. 34:101-108. 1998
- Altering flavor profiles in onion (Allium cepa L) root cultures through directed biosynthesis. Biotechnology Progress. 13:506-510. 1997
- Combined use of six well polystyrene plates and thin layer chromatography for rapid development of optimal plant cell culture processes: Application to taxane production by Taxus sp.. Plant Cell Reports. 16:600-604. 1997
- Effect of elevated oxygen and glutamine levels on foreign protein production at high cell densities using the insect cell-baculovirus expression system. Biotechnology and Bioengineering. 54:142-152. 1997
- Evaluation of the utility of bacterial extracellular polymers for treatment of metal-contaminated soils: Polymer persistence, mobility, and the influence of lead. Water Research. 31:2827-2839. 1997
- Increased virus production in suspension culture by a Trichoplusia ni cell line in serum-free media. Biotechnology Progress. 13:805-809. 1997
- Inducing single-cell suspension of BTI-TN5B1-4 insect cells .2. The effect of sulfated polyanions on baculovirus infection. Biotechnology and Bioengineering. 54:206-220. 1997
- Large-scale plant cell culture. Current Opinion in Biotechnology. 8:154-159. 1997
- Mathematical model of the trafficking of acid-dependent enveloped viruses: Application to the binding, uptake, and nuclear accumulation of baculovirus. Biotechnology and Bioengineering. 54:468-490. 1997
- Optimization of an assay for baculovirus titer and design of regimens for the synchronous infection of insect cells. Biotechnology Progress. 13:14-24. 1997
- Overview of yield improvement strategies for secondary metabolite production in plant cell cultures.. Abstracts of Papers of the American Chemical Society. 213. 1997
- Rapid initiation of suspension cultures of Trichoplusia ni insect cells (TN 5B-1-4) using heparin. Biotechnology Techniques. 11:237-240. 1997
- The production of paclitaxel and other taxanes in Taxus canadensis suspension cell cultures elicited with methyl jasmonate.. Plant Physiology. 114:1182-1182. 1997
- A low-cost serum-free medium for the BTI-Tn5B1-4 insect cell line.. Abstracts of Papers of the American Chemical Society. 211. 1996
- A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats. Annals of Biomedical Engineering. 24:305-320. 1996
- A self-regulating cell culture analog device to mimic animal and human toxicological responses. Biotechnology and Bioengineering. 52:45-60. 1996
- Determination of iron colloid size distribution in the presence of suspended cells: Application to iron deposition onto a biofilm surface. Water Research. 30:2413-2423. 1996
- Inducing single-cell suspension of BTI-Tn5B1-4 insect cells with polymers and enhancement of recombinant protein production.. Abstracts of Papers of the American Chemical Society. 211. 1996
- Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor. Enzyme and Microbial Technology. 19:256-260. 1996
- Metabolic inhibitors, elicitors, and precursors as tools for probing yield limitation in taxane production by Taxus chinensis cell cultures. Biotechnology Progress. 12:457-465. 1996
- Microscale-based modeling of polynuclear aromatic hydrocarbon transport and biodegradation in soil. Biotechnology and Bioengineering. 51:1-14. 1996
- Modeling oligotrophic biofilm formation and lead adsorption to biofilm components. Environmental Science & Technology. 30:2027-2035. 1996
- Possible role of arachidonic acid in stress-induced cytochrome P450IA1 activity. Biotechnology Progress. 12:847-854. 1996
- Taxol production in suspension cultures of Taxus baccata. Plant Cell Tissue and Organ Culture. 44:95-102. 1996
- A Cell-Culture Analog of Rodent Physiology - Application to Naphthalene Toxicology. Toxicology in Vitro. 9:307-316. 1995
- A Model of the Binding, Entry, Uncoating, and Rna-Synthesis of Semliki-Forest-Virus in Baby Hamster-Kidney (Bhk-21) Cells. Biotechnology and Bioengineering. 46:485-496. 1995
- A Simple-Model to Predict the Effectiveness of Molecules That Block Attachment of Human Rhinoviruses and Other Viruses. Biotechnology Progress. 11:164-170. 1995
- Elicitation of Taxus sp cell cultures for production of taxol. Biotechnology Letters. 17:1343-1346. 1995
- Induction of Cytochrome P-450ia1 Activity in Response to Sublethal Stresses in Microcarrier-Attached Hep G2 Cells. Biotechnology Progress. 11:659-663. 1995
- Lead Distribution in a Simulated Aquatic Environment - Effects of Bacterial Biofilms and Iron-Oxide. Water Research. 29:1934-1944. 1995
- Mobilization of Adsorbed Cadmium and Lead in Aquifer Material by Bacterial Extracellular Polymers. Water Research. 29:421-430. 1995
- Model of a Split-Flow Airlift Bioreactor for Attachment-Dependent, Baculovirus-Infected Insect Cells. Biotechnology Progress. 11:412-419. 1995
- Modeling Interactions of Toxic Metals with Suspended Bacterial-Cells, Extracellular Polymer and Biofilms in a Simulated Fresh-Water Environment. Abstracts of Papers of the American Chemical Society. 209. 1995
- Possible Involvement of the Ah Receptor in the Induction of Cytochrome P-450ia1 under Conditions of Hydrodynamic Shear in Microcarrier-Attached Hepatoma-Cell Lines. Biochemical and Biophysical Research Communications. 208:144-152. 1995
- Taxol Production in Bioreactors - Kinetics of Biomass Accumulation, Nutrient-Uptake, and Taxol Production by Cell-Suspensions of Taxus-Baccata. Biotechnology and Bioengineering. 47:666-676. 1995
- Trace-Metal Mobilization in Soil by Bacterial Polymers. Environmental Health Perspectives. 103:53-58. 1995
- Bioreactor engineering as an enabling technology to tap biodiversity. The case of taxol. Ann N Y Acad Sci. 745:455-61. 1994
- Deposition of Colloidal Iron onto a Biofilm Surface - Determination of the Particle-Size Distribution of Colloidal Iron(Iii) Oxyhydroxide in the Presence of Suspended Bacterial-Cells. Abstracts of Papers of the American Chemical Society. 208. 1994
- Effects of Medium Manipulation on Growth and Taxol Production in Taxus Sp. Abstracts of Papers of the American Chemical Society. 207. 1994
- Interactions of Microbial Biofilms with Toxic Trace-Metals .2. Prediction and Verification of an Integrated Computer-Model of Lead-(Ii) Distribution in the Presence of Microbial Activity. Biotechnology and Bioengineering. 44:232-239. 1994
- Mass-Transfer of Gaseous Components - Implications for Plant-Cell Culture. Abstracts of Papers of the American Chemical Society. 207. 1994
- Ribosomal-Protein Limitations in Escherichia-Coli under Conditions of High Translational Activity. Biotechnology and Bioengineering. 43:388-398. 1994
- Structured Model of Genetic-Control Via the Lac Promoter in Escherichia-Coli. Biotechnology and Bioengineering. 43:399-410. 1994
- A Computer-Model for Intracellular Ph Regulation in Chinese-Hamster Ovary Cells. Biotechnology Progress. 9:374-384. 1993
- Comparative Recombinant Protein-Production of 8 Insect-Cell Lines. In Vitro Cellular & Developmental Biology-Animal. 29A:388-390. 1993
- Continuous, High-Level Production and Excretion of a Plasmid-Encoded Protein by Escherichia-Coli in a 2-Stage Chemostat. Biotechnology and Bioengineering. 41:937-946. 1993
- Description of Time-Varying Desorption-Kinetics - Release of Naphthalene from Contaminated Soils. Environmental Science & Technology. 27:2397-2403. 1993
- Effect of Trichoplusia-Ni Bti-Tn 5b1-4 Cell-Density on Human Secreted Alkaline-Phosphatase Production. Biotechnology Letters. 15:1007-1012. 1993
- Effects of Plasmid Copy Number and Runaway Plasmid Replication on Overproduction and Excretion of Beta-Lactamase from Escherichia-Coli. Biotechnology Progress. 9:31-39. 1993
- Giving up on Taxol. Bio-Technology. 11:1204-1204. 1993
- Production of Human Alkaline-Phosphatase, a Secreted, Glycosylated Protein, from a Baculovirus Expression System and the Attachment-Dependent Cell-Line Trichoplusia-Ni Bti-Tn 5b1-4 Using a Split-Flow, Airlift Bioreactor. Biotechnology Progress. 9:675-678. 1993
- Use of a Simple Mathematical-Model to Predict the Behavior of Escherichia-Coli Overproducing Beta-Lactamase within Continuous Single-Stage and 2-Stage Reactor Systems. Biotechnology and Bioengineering. 42:557-570. 1993
- A Single-Cell Model for Cho Cells. Annals of the New York Academy of Sciences. 665:152-187. 1992
- Amino-Acid Supplementation Decreases Plasmid Retention in Escherichia-Coli. Biotechnology and Bioengineering. 40:1197-1202. 1992
- Equilibrium and Kinetic-Analysis of Autographa-Californica Nuclear Polyhedrosis-Virus Attachment to Different Insect Cell-Lines. Journal of General Virology. 73:3185-3194. 1992
- Escherichia-Coli Host-Cell Modifications in Continuous Culture Affecting Heterologous Protein Overproduction - a Population-Dynamics Study. Biotechnology Progress. 8:340-346. 1992
- Expression of Human Epidermal Growth-Factor by Escherichia-Coli in Continuous Culture. Biotechnology Letters. 14:339-344. 1992
- Screening of Insect Cell-Lines for the Production of Recombinant Proteins and Infectious Virus in the Baculovirus Expression System. Biotechnology Progress. 8:391-396. 1992
- Studies on Serum-Free Culture of Insect Cells for Virus Propagation and Recombinant Protein-Production. Journal of Invertebrate Pathology. 59:46-53. 1992
- Studies on serum-free culture of insect cells for virus propagation and recombinant protein production. Journal of Invertebrate Pathology. 59:46-53. 1992
- Baculovirus Defective Interfering Particles Are Responsible for Variations in Recombinant Protein-Production as a Function of Multiplicity of Infection. Biotechnology Letters. 13:483-488. 1991
- Convective Mass-Transfer in Large Porous Biocatalysts - Plant Organ-Cultures. Biotechnology Progress. 7:195-199. 1991
- Different Shake Flask Closures Alter Gas-Phase Composition and Ajmalicine Production in Catharanthus-Roseus Cell-Suspensions. Biotechnology Techniques. 5:173-178. 1991
- Economic-Evaluation of a Multicompartment Bioreactor for Ethanol-Production Using Insitu Extraction of Ethanol. Applied Biochemistry and Biotechnology. 28-9:571-588. 1991
- Enhanced Anthocyanin Production in Grape Cell-Cultures. Plant Science. 78:107-120. 1991
- Experimental Apparatus for Selection of Adherent Microorganisms under Stringent Growth-Conditions. Applied and Environmental Microbiology. 57:1987-1996. 1991
- Kinetic-Analysis of the Effects of Plasmid Multimerization on Segregational Instability of Cole1 Type Plasmids in Escherichia-Coli B/R. Biotechnology and Bioengineering. 37:1076-1086. 1991
- Prediction of Effects of Amino-Acid Supplementation on Growth of Escherichia-Coli B/R. Biotechnology and Bioengineering. 37:708-715. 1991
- Protein-Production (Beta-Galactosidase) from a Baculovirus Vector in Spodoptera-Frugiperda and Trichpolusia-Ni Cells in Suspension-Culture. Biotechnology Letters. 13:265-270. 1991
- A Structured, Segregated Model for Genetically Modified Escherichia-Coli-Cells and Its Use for Prediction of Plasmid Stability. Biotechnology and Bioengineering. 36:581-592. 1990
- A simple membrane reactor to obtain high cell density and plasmid encoded protein production from Escherichia coli. Biotech. Techn. 4:73-78. 1990
- Analysis of Pbr322 Replication Kinetics and Its Dependency on Growth-Rate. Biotechnology and Bioengineering. 36:233-242. 1990
- Bioreactor development for production of viral pesticides or heterologous proteins in insect cell cultures. Ann N Y Acad Sci. 589:399-422. 1990
- Continuous Operation of a Pressure-Cycled Membrane Bioreactor. Biotechnology Progress. 6:286-291. 1990
- Development of a Single Cell Model for Cho Cells and Its Application in the Study of Intracellular Ph Regulation. Abstracts of Papers of the American Chemical Society. 199. 1990
- Effects of Temperature on Escherichia-Coli Overproducing Beta-Lactamase or Human Epidermal Growth-Factor. Applied and Environmental Microbiology. 56:104-111. 1990
- General-Analysis of Receptor-Mediated Viral Attachment to Cell-Surfaces. Biophysical Journal. 58:1501-1516. 1990
- Mathematical-Modeling and Simulations of Membrane Bioreactor Extractive Fermentations. Biotechnology Progress. 6:362-369. 1990
- Peg-Enhanced, Electric Field-Induced Fusion of Tonoplast and Plasmalemma of Grape Protoplasts. Plant Cell Tissue and Organ Culture. 23:107-114. 1990
- Production of Extracellular and Cell-Associated Biopolymers by Pseudomonas-Atlantica. Biotechnology Letters. 12:449-454. 1990
- A Mathematical-Model for the Growth of a Single Cell of Escherichia-Coli on a Glucose Glutamine Ammonium Medium. Biotechnology and Bioengineering. 33:1117-1126. 1989
- Adsorption of Nonpolar Solutes onto Neutral Polymeric Sorbents. Separation Science and Technology. 24:457-465. 1989
- Effect of Surface-Chemistry on Receptor-Mediated Viral Attachment to Cell-Surfaces. Abstracts of Papers of the American Chemical Society. 198. 1989
- Stimulation of Ajmalicine Production and Excretion from Catharanthus-Roseus - Effects of Adsorption Insitu, Elicitors and Alginate Immobilization. Applied Microbiology and Biotechnology. 30:475-481. 1989
- Structured Model for Saccharomyces-Cerevisiae. Chemical Engineering Science. 44:2017-2030. 1989
- Bioreactor Considerations for Secondary Metabolite Production from Plant-Cell Tissue-Culture - Indole Alkaloids from Catharanthus-Roseus. Biotechnology and Bioengineering. 31:905-912. 1988
- Effect of Alkaline-Medium on the Production and Excretion of Beta-Lactamase by Escherichia-Coli. Biotechnology Letters. 10:377-382. 1988
- Flavor Compound Production from Root Cultures of Allium Species. Abstracts of Papers of the American Chemical Society. 195. 1988
- Getting the Product out - a Multimembrane Bioreactor with Integral Product Recovery. Chemtech. 18:680-685. 1988
- Insitu Adsorption for Enhanced Alkaloid Production by Catharanthus-Roseus. Biotechnology Letters. 10:187-192. 1988
- Microbial-Growth Model Based on Carbon Material Balance and Carbon-Dioxide Evolution Rate. Abstracts of Papers of the American Chemical Society. 195. 1988
- Release of Periplasmic Enzymes and Other Physiological-Effects of Beta-Lactamase Overproduction in Escherichia-Coli. Biotechnology and Bioengineering. 32:741-748. 1988
- Selective Adsorption of Plant-Products. Biotechnology and Bioengineering. 31:922-928. 1988
- Stimulation of Ajmalicine Production and Excretion from Catharanthus-Roseus. Abstracts of Papers of the American Chemical Society. 196. 1988
- A Mathematical-Model for Prediction of Plasmid Copy Number and Genetic Stability in Escherichia-Coli. Biotechnology and Bioengineering. 30:389-397. 1987
- Biostability in Ammonium-Limited Cultures of Escherichia-Coli-B/R. Chemical Engineering Communications. 58:185-194. 1987
- Elimination of Diffusional Limitations in a Membrane Entrapped Cell Reactor by Pressure Cycling. Biotechnology Progress. 3:259-264. 1987
- Growth behavior and prediction of copy number and retention of ColE1-type plasmids in E. coli under slow growth conditions. Ann N Y Acad Sci. 506:384-95. 1987
- Growth-Behavior and Prediction of Copy Number and Retention of Cole1-Type Plasmids in Escherichia-Coli under Slow Growth-Conditions. Annals of the New York Academy of Sciences. 506:384-395. 1987
- Immobilization of Cells by Entrapment in Membrane Reactors. Methods in Enzymology. 135:372-387. 1987
- Trace-Metal Interactions with Microbial Biofilms in Natural and Engineered Systems. Crc Critical Reviews in Environmental Control. 17:273-306. 1987
- A Computer-Model for the Growth and Differentiation of a Fungal Colony on Solid Substrate. Biotechnology and Bioengineering. 28:405-416. 1986
- Bioreactors for Immobilized Plant-Cell Cultures. Annals of the New York Academy of Sciences. 469:270-278. 1986
- Localization of Inclusion-Bodies in Escherichia-Coli Overproducing Beta-Lactamase or Alkaline-Phosphatase. Applied and Environmental Microbiology. 52:1157-1161. 1986
- Mathematical-Model for the Control of Cole1 Type Plasmid Replication. Plasmid. 16:204-212. 1986
- Multimembrane Bioreactor for Extractive Fermentation. Biotechnology Progress. 2:53-60. 1986
- Bioreactor for the Study of Defined Interactions of Toxic Metals and Biofilms. Applied and Environmental Microbiology. 50:1155-1161. 1985
- Continuous Immobilized Recombinant Protein-Production from Escherichia-Coli Capable of Selective Protein Excretion - a Feasibility Study. Biotechnology Progress. 1:75-79. 1985
- Continuous Production of Plasmid-Encoded Proteins from Immobilized Escherichia-Coli. Abstracts of Papers of the American Chemical Society. 190. 1985
- Design of a System for the Control of Low Dissolved-Oxygen Concentrations - Critical Oxygen Concentrations for Azotobacter-Vinelandii and Escherichia-Coli. Biotechnology and Bioengineering. 27:151-155. 1985
- Invited Review on the Use of Chemically Structured Models for Bioreactors. Chemical Engineering Communications. 36:161-189. 1985
- Predicting Threshold Concentrations of Organic Substrates for Bacterial-Growth. Journal of Theoretical Biology. 114:1-8. 1985
- Simulation of Cfstr through Development of a Mathematical-Model for Anaerobic Growth of Escherichia-Coli Cell-Population. Biotechnology and Bioengineering. 27:1051-1055. 1985
- Simulation of the Growth-Pattern of a Single Cell of Escherichia-Coli under Anaerobic Conditions. Biotechnology and Bioengineering. 27:1027-1035. 1985
- A Finite Representation Model for an Asynchronous Culture of Escherichia-Coli. Biotechnology and Bioengineering. 26:877-884. 1984
- Computer-Model for Glucose-Limited Growth of a Single Cell of Escherichia-Coli B/R-A. Biotechnology and Bioengineering. 26:203-216. 1984
- Double-Substrate-Limited Growth of Escherichia-Coli. Biotechnology and Bioengineering. 26:1398-1401. 1984
- Environmental Parameters Influencing Phenolics Production by Batch Cultures of Nicotiana-Tabacum. Biotechnology and Bioengineering. 26:111-120. 1984
- Multistage Continuous Culture to Examine Secondary Metabolite Formation in Plant-Cells - Phenolics from Nicotiana-Tabacum. Biotechnology and Bioengineering. 26:27-36. 1984
- Prospects and Problems in the Large-Scale Production of Metabolites from Plant-Cell Tissue-Cultures. Journal of the American Oil Chemists Society. 61:648-648. 1984
- Testing of a Potential Mechanism for Escherichia-Coli Temporal Cycle Imprecision with a Structural Model. Journal of Theoretical Biology. 106:577-585. 1984
- Entrapped Plant-Cell Tissue-Cultures. Annals of the New York Academy of Sciences. 413:373-382. 1983
- Heat and Mass-Transfer Effects in Static Solid-Substrate Fermentations - Design of Fermentation Chambers. Biotechnology and Bioengineering. 25:929-938. 1983
- Mathematical-Models of the Growth of Individual Cells - Tools for Testing Biochemical-Mechanisms. Acs Symposium Series. 207:93-133. 1983
- On the Nonideality of Chemostat Operation Using Plant-Cell Suspension-Cultures. Canadian Journal of Botany-Revue Canadienne De Botanique. 60:692-700. 1982
- The Feasibility of an Activated Sludge-Ultrafiltration Unit for Use in Closed Ecological Life Support Systems - Experimental System and Preliminary-Results. Abstracts of Papers of the American Chemical Society. 184. 1982
- A Mixed Yeast-Bacteria Process for the Aerobic Conversion of Poultry Waste into Single-Cell Protein. Biotechnology Letters. 3:409-414. 1981
- Multiple Steady-State Phenomena within Enzyme Reactors - the Enzyme Reaction with 2 Substrates. Biotechnology and Bioengineering. 23:939-952. 1981
- The Measurement of Effective Substrate Diffusivities within Whole Cell-Suspensions Using a Diffusion-Limited Hollow Fiber Reactor. Journal of Chemical Technology and Biotechnology. 31:226-234. 1981
- Whole-Cell Hollow-Fiber Reactor - Transient Substrate Concentration Profiles. Biotechnology and Bioengineering. 23:447-450. 1981
- Continuous Aerobic Conversion of Poultry Waste into Single-Cell Protein Using a Single Reactor - Kinetic-Analysis and Determination of Optimal Conditions. Biotechnology and Bioengineering. 22:1567-1600. 1980
- Continuous Aerobic Conversion of Poultry Waste into Single-Cell Protein Using a Single Reactor: Kinetic Analysis and Determination of Optimal Conditions. Biotechnology and Bioengineering. 22:1567-1600. 1980
- Evaluation of Various Flocculants for the Recovery of Biomass Grown on Poultry Waste. Agricultural Wastes. 2:1-12. 1980
- The Effect of Variations in Carbon and Nitrogen Concentrations on Phenolics Formation in Plant-Cell Suspension-Cultures. Journal of Natural Products. 43:87-96. 1980
- Generalized Differential Specific Rate Equation for Microbial-Growth. Biotechnology and Bioengineering. 21:1871-1875. 1979
- Possibility of Stabilizing a Simple Negative Feedback-Control System by Increasing Controller Gain on a Pid Controller. AIChe Journal. 25:373-376. 1979
- Process for Aerobic Conversion of Poultry Manure into High-Protein Feedstuff. Biotechnology and Bioengineering. 21:19-38. 1979
- Process for the Aerobic Conversion of Poultry Manure into High-Protein Feedstuff. Biotechnology and Bioengineering. 21:19-38. 1979
- Whole Cell Hollow Fiber Reactor .3. Comparison of Reactor Efficiencies Using a Hlavacek Lumping Technique. Chemical Engineering Science. 34:1273-1282. 1979
- Whole-Cell Hollow-Fiber Reactor - Effectiveness Factors. Biotechnology and Bioengineering. 21:1725-1748. 1979
- Electronic Measurement of Plant-Cell Number and Size in Suspension Culture. Journal of Experimental Botany. 29:511-523. 1978
- Generality of Methods to Obtain Single-Cell Plant Suspension Cultures. Canadian Journal of Botany-Revue Canadienne De Botanique. 56:2521-2527. 1978
- Mathematical-Models for Hollow-Fiber Enzyme Reactors. Biotechnology and Bioengineering. 20:1541-1556. 1978
- Microbial Processing of Poultry Manure for Feeding to Poultry. Poultry Science. 57:1116-1116. 1978
- Nutritional-Evaluation of a Single Cell Protein from Poultry Manure. Poultry Science. 57:1144-1144. 1978
- Rapid Quantitative Method to Measure Growth of Plant-Cell Suspension Cultures. Canadian Journal of Botany-Revue Canadienne De Botanique. 56:2340-2343. 1978
- Urocanic Acid Production Using Whole Cells Immobilized in a Hollow Fiber Reactor. Biotechnology and Bioengineering. 20:217-230. 1978
- Predictions of Cellular Growth-Patterns by a Feedback Model. Journal of Theoretical Biology. 68:415-435. 1977
- Cell size as an indicator of changes in intracellular composition of Azotobacter vinelandii. Can J Microbiol. 21:927-35. 1975
- Diffusive and electrostatic effects with insolubilized enzymes subject to substrate inhibition. Journal of Theoretical Biology. 41:347-56. 1973
- Hydrodynamic Focusing and Electronic Cell-Sizing Techniques. Applied Microbiology. 24:384-388. 1972
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document part
featured in archived article
- Biomedical engineering grad students to help rural teachers communicate science
- Cornell engineers and Weill Cornell neurosurgeons gather to forge partnership for medical advancement
- Engineering professors Hopcroft and Shuler to receive honorary doctorates
- For researchers in Weill Hall, collaboration between Ithaca and New York City is central
- Research Without Boundaries, College of Engineering
- Symposium on nanomedicine to introduce new nanotech facility office at WCMC
- Weill Hall, life science research center for ideas and collaboration, is open for business
speaker at Cornell event
Teaching
teaching activities
- BME-4900: Independent Undergraduate Project in Biomedical Engineering - Spring 2013
- BME-7030: Graduate Student Teaching Experience - Spring 2013
- BME-7900: Biomedical Engineering Seminar - Spring 2013
- CHEME-4900: Undergraduate Projects in Chemical Engineering - Spring 2013
- TOX-8900: Master's Thesis and Research - Spring 2013
- TOX-9900: Doctoral Thesis and Research - Spring 2013
- BME-4900: Independent Undergraduate Project in Biomedical Engineering - Fall 2012
- BME-7900: Biomedical Engineering Seminar - Fall 2012
- BME-8600: Doctoral Research Rotations in Biomedical Engineering - Fall 2012
- CHEME-4900: Undergraduate Projects in Chemical Engineering - Fall 2012
- TOX-8900: Master's Thesis and Research - Fall 2012
- TOX-9900: Doctoral Thesis and Research - Fall 2012
- BME-4900: Independent Undergraduate Project in Biomedical Engineering - Spring 2012
- BME-7030: Graduate Student Teaching Experience - Spring 2012
- BME-7900: Biomedical Engineering Seminar - Spring 2012
- CHEME-4900: Undergraduate Projects in Chemical Engineering - Spring 2012
- TOX-8900: Master's Thesis and Research - Spring 2012
- TOX-9900: Doctoral Thesis and Research - Spring 2012
- BME-4900: Independent Undergraduate Project in Biomedical Engineering - Fall 2011
- BME-7900: Biomedical Engineering Seminar - Fall 2011
- BME-8600: Doctoral Research Rotations in Biomedical Engineering - Fall 2011
- CHEME-4900: Undergraduate Projects in Chemical Engineering - Fall 2011
- TOX-8900: Master's Thesis and Research - Fall 2011
- TOX-9900: Doctoral Thesis and Research - Fall 2011
Service
Background
education and training
- Ph.D. in Chemical Engineering, UNIVERSITY OF MINNESOTA 1973
- B.S. in Chemical Engineering, UNIVERSITY OF NOTRE DAME 1969
awards and honors
- 2011 Robert A. Pritzker Distinguished Lecture Award, 2011
- Honorary Doctorate, 2008
- Named as one of "Thirty Authors of Ground Breaking Chemical Engineering Books", 2008
- Named as one of "One Hundred Engineers of the Modern Era", 2008
- Fellow, 2007
- The Academy of Chemical Engineers Lectureship, 2006
- The John C. and Florence W. Holtz Lecturer, 2005
- Kelly Distinguished Lecturer, 2005
- Asia Pacific Biochemical Engineering Conference Award, 2005
- James E. Bailey Award, 2005
- W.K. Lewis Award, 2003
- W.N. Lacey Lectureship in Chemical Engineering, 2001
- James M. & Marsha D. McCormick Advising Award, 2001
- NYSTAR Distinguished Professor, 2001
- Paper (Domach et al., 1984) selected for 40th Anniversary Issue of Biotechnol Bioeng, 2000
- Reilly Lectureship in Chemical Engineering, 1998
- Amgen Award in Biochemical Engineering, 1997
- Elected Fellow, 1997
- American Academy of Arts and Sciences, 1996
- College of Engineering Teaching Award, 1996
- Pirkey Lecturer, 1995
- Elected an Inaugural Fellow of the American Institute for Medical and Biological Engineering, 1992
- Professional Progress Award for Outstanding Progress in Chem. Eng, 1991
- Class I NASA Tech Briefs (Patent Application on "Apparatus and Process to Eliminate Diffusional Limitations in a Membrane Bio-reactor by pressure Cycling"), 1990
- College of Engineering Honor Award, 1989
- National Academy fo Engineering, 1989
- AIChE Food, Pharmaceutical, & Bioengineering Division Award, 1989
- Class I NASA Tech Briefs (Patent Applications on "Use of Inhibitory Solvents in Multi-Membrane Reactor"), 1988
- Recipient of the Marvin J. Johnson Award, 1986
- Outstanding Paper Presentation Award, 1984
- Colburn Lecturer, 1982
- Excellence in Teaching Award, 1978
Other
college
- ENG
name prefix
- Dr.