Highly proliferative, relatively undifferentiated canine osteosarcoma cell lines and a highly differentiated epithelial cell in which proliferation is developmentally regulated to study cell proliferation and differentiation

Established five canine osteosarcoma cell lines from independent animals with the goal of identifying the oncogenes, tumor suppressor genes, and signaling pathways that are aberrantly regulated and the mechanisms by which these mutant proteins and pathways control cellular proliferation and differentiation

Screening cDNA libraries to identify and study genes that regulate type 2 cell proliferation and differentiation