Networks
McDonough, Patrick L
Associate Professor
Positions
- Associate Professor, Population Medicine and Diagnostic Sciences (VTPMD), College of Veterinary Medicine
- Academic Director, Animal Health Diagnostic Center, College of Veterinary Medicine
- Affiliations
- Research
- Publications
- Teaching
- Background
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Affiliations
other Cornell affiliations
member of
- David R. Atkinson Center for a Sustainable Future (ACSF) Faculty Fellow
Research
research overview
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- Infectious diseases
- Microbiology of the Enterobacteriaceae and the microbial ecology of the intestinal tract
- Virulence mechanisms and pathogenesis of enteric bacterial infections, especially salmonellae, Helicobacter, Clostridium perfringens, Campylobacter and E. coli
- Immunity to Salmonella infections
- Salmonella epidemiology and control programs
- Antimicrobial resistance in bacteria
- Development of new diagnostic assays and media for use in veterinary clinical microbiology
- Development of biosensors for the rapid detection of microorganisms
- Use of fatty acid methyl ester analysis (FAME) in the identification of bacteria and fungi
- Molecular epidemiology of microorganisms (using fingerprinting techniques such as FAME, PFGE, ribotyping)
Publications
individual publications
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academic article
- Equine stomach harbors an abundant and diverse mucosal.. Applied Environmental Microbiology. 78:2522-2532. 2012
- Prevalence of multidrug resistance is higher among bovine than human Salmonella Newport, Typhimurium and 4,5,12:i:- isolates, but differs by serotype and geographic region in the US. Applied and Environmental Microbiology. 76:5947-5959. 2010
- Pulsed-field Gel Electrophoresis diversity of human and bovine clinical Salmonella isolates. Foodborne Pathogens and Disease. 7:707-717. 2010
- Temporal clusters of bovine Salmonella cases at a veterinary medical teaching hospital, 1996-2007. Vector borne and Zoonotic Diseases. 10:471-479. 2010
- Fecal Shedding, antimicrobial resistance, and serological response to Salmonella Typhimurium in dairy calves. Journal of the American Veterinary Medical Association. 235:739-748. 2009
- Multilocus variable-number tandem-repeat method for typing Salmonella enterica serovar Newport. Journal of Clinical Microbiology. 47:1934-1938. 2009
- Salmonella 4,5,12:i:-: an emerging Salmonella serotype that represents multiple distinct clones. Journal of Clinical Microbiology. 47:3546-3556. 2009
- Ecology and transmission of Listeria monocytogenes infecting ruminants and in the farm environment. Applied and Environmental Microbiology. 70:4458-4467. 2004
- Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in their pathogenic potential. Infect. Immun. 65:2707-2716. 1997
- Ribotype diversity of Listeria monocytogenes strains associated with outbreaks of listeriosis in ruminants. Journal of Clinical Microbiology. 34:1086-1090. 1996
selected publications listing
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Peer-reviewed Articles
- Gerold A, E Scanziani, D Dailidiene, G Dalilide, J Adaska, PL McDonough, Y-F Chang, DE Berg, KW Simpson. Helicobacter pylori infection in cats: natural and experimental infection, strain characterization and eradication. Submitted
- Dheenadhayalan V, KS Shin, CF Chang, CD Chang, SP McDonough, PL McDonough, S Shin, DH Lein, Y-F Chang. Cloning and characterization of the genes coding for antigen 85A, 85B and 85C of Mycobacterium avium subsp. Paratuberculosis. FEMS Microbiol Letters Submitted
- Raghavan PUM, SP McDonough, SC Barr, TJ Divers, P McDonough, Y-F Chang. Cloning and molecular characterization of an immunogenic 90-kDa membrane protein of Leptospira interrogans. Infect Immun Submitted
- Warnick LD, K Kanistanon, PL McDonough, L Power. Factors related to fecal shedding of Salmonella enterica subsp enterica group B in New York dairy farms with a history of clinical salmonellosis. Preventive Vet Med Submitted
- McDonough PL, CA Rossiter, Y-F Chang, SJ Shin, H Mohammed, S Stehman, J Dunlop, C Ramos, and DH Lein. Fatty acid characterization of Mycobacterium avium subsp. paratuberculosis - a useful tool assessing diversity of isolates. Appl Environ Microbiol Submitted
- Simpson KW, D Strauss-Ayali, RK Straubinger R., E Scanziani, PL McDonough, AF Straubinger, M Esteves, JG Fox, Y-F Chang, C Domenghini, N Arebi, and J Calam. 2001. Helicobacter pylori infection in the cat: evaluation of gastric colonization, inflammation and function. Helicobacter 6:1-14
- Jeffers GT, JL Bruce, PL McDonough, J Scarlett, KJ Boor, and M Wiedmann. 2001. Comparative genetic characterization of Listeria monocytogenes isolates from human and animal listeriosis cases. Microbiol 147:1095-1104
- Hassan L, HO Mohammed, and PL McDonough. 2001. Management and milking practices associated with the presence of Listeria monocytogenes in dairy farms in New York State. Prev Vet Medicine 51:63-73
- Spain CV, JM Scarlett, S Wade, and P McDonough. 2001. Prevalence of Enteric Zoonotic Agents in Cats Less Than One?year Old in Central New York State. J Vet Internal Med 15:33-38
- Hassan L, HO Mohammed, PL McDonough, RN Gonzalez. 2000. A cross-sectional study on the prevalence of Listeria monocytogenes and Salmonella in the New York Dairy Herds. J Dairy Sci 83:2441-2447
- Rurangirwa FR, CA Teitzel, J Cui, DM French, PL McDonough, and T. Besser. 2000. Streptococcus didelphis, sp. nov., a catalase positive streptococcus isolated from opossums Didelphis virginiana) with suppurative dermatitis and liver fibrosis. International J of Systematic and Evolutionary Microbiol 50:759-765
- Simpson KW, D Straus-Ayali, E Scanziani, RK Straubinger, PL McDonough, AF Straubinger, Y-F Chang, C Domeneghini, N Arebi, and J Calam. 2000. Helicobacter felis infection is associated with lymphoid follicular hyperplasia and mild gastritis but normal gastric secretory function in cats. Infect Immun 68:779-790.
- McDonough PL, CA. Rossiter, RB. Rebhun, S M. Stehman, DH. Lein, SJ. Shin. 2000. Prevalence of Escherichia coli O157:H7 from cull dairy cows in New York State and comparison of culture methods used during preharvest food safety investigations. J Clin Microbiol 38: 318-322.
Book chapters
- McDonough PL. 2001. Leptospirosis in dogs - Current Status, 6 pg., In: Recent Advances in Canine Infectious Diseases, LE Carmichael (ed.), Publisher: International Veterinary Information Service - IVIS (http://www.ivis.org)
- McDonough PL. 2000. Tularemia, p. 1271, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL. 2000. Tetanus, p. 1238-1239, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL. 2000. Plague (Yersinia pestis), p. 1080, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL., and K Simpson. 2000. Campylobacteriosis, p. 514, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL. 2000. Leptospirosis, pp. 894-895, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL, and Simpson KW. 2000. Colibacillosis, pp. 570-571, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL. 2000. Salmonellosis, pp. 1182-1183, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, eds., 2nd Edition, Lippincott Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Tularemia, p. 1121, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Plague, p. 942, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Tetanus, p. 1095, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Campylobacteriosis, p. 412, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Leptospirosis, pp. 768-769, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Colibacillosis, pp. 464-465, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL. 1996. Salmonellosis, pp. 1050-1051, In: The 5 Minute Veterinary Consult: Canine and Feline, LP Tilley, FWK Smith Jr, AC MacMurray, eds., Williams and Wilkins, Baltimore, MD.
- McDonough PL, and CN Vaughn. 1996. Bacterial Diseases, pp 294-304, Chapter 30, In: The Cornell Book of Cats - A Comprehensive Medical Reference for Every Cat and Kitten, 2nd Edition, M Siegal, ed, Villard Books, NY.
Teaching
Background
education and training
- Ph.D. in Bacteriology 1985
- M.S. in Bacteriology, Cornell University 1976
- B.S. in Biology, Albright College 1973