• joint pathobiology and cartilage repair with growth factor gene-enhanced chondrocyte and stem cell transplantation techniques
• genetic characterization of OCD in animals and man using microarray expression studies
• clinical application of growth factor recombinant proteins and gene therapy for improved joint, tendon, and bone repair

• Wilke MM, Nydam DV, Nixon AJ. Enhanced early chondrogenesis in articular defects following arthroscopic mesenchymal stem cell implantation in an equine model. J Orthop Res 25:913-925, 2007.
• Goodrich LR, Nixon AJ. Genetic modification of chondrocytes with insulin-like growth factor enhances cartilage healing in an equine model. J Bone Joint Surg, Br 89:672-685, 2007.
• Morisset S, Frisbie DD, Robbins PD, Nixon AJ, McIlwraith CW. IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects. Clin Orthop Relat Res 462:221-228, 2007.
• Nixon AJ, Goodrich LR, Scimeca MS, Witte TH, Schnabel LV, Watts AE, Robbins PD. Gene therapy in musculoskeletal repair. Ann NY Acad Sci 1117:310-327, 2007.
• Zaidi N, Nixon AJ. Stem cell therapy in bone repair and regeneration. Ann NY Acad Sci 1117:62-72 2007.
• Gratz KR, Wong VW, Chen AC, Fortier LA, Nixon AJ, Sah RL. Biomechanical assessment of tissue retrieved after in vivo cartilage defect repair: tensile modulus of repair tissue and integration with host cartilage. J Biomech 39:138-146, 2006.
• Goodrich LR, Nixon AJ. Medical treatment of osteoarthritis in the horse - A review. Vet J 171:51-69, 2006.
• Dahlgren LA, Mohammed HO, Nixon AJ. Expression of insulin-like growth factor binding proteins in healing tendon lesions. J Orthop Res 24:183-192, 2006.
• Goodrich LR, Brower-Toland BD, Warnick L, Robbins PD, Evans CH, Nixon AJ. Direct adenovirus-mediated IGF-I gene transduction of synovium induces persisting synovial fluid IGF-I ligand elevations. Gene Ther 13:1253-1262, 2006; Epub 2006 May 18.
• Semevolos SA, Nixon AJ, Fortier LA, Strassheim ML, Haupt J. Age-related expression of molecular regulators of hypertrophy and maturation in articular cartilage. J Orthop Res 24:1773-1781, 2006.
• Donnelly BP, Nixon AJ, Haupt JL, Dahlgren LA. Nucleotide structure of equine platelet-derived growth factor-A and -B and expression in horses with induced acute tendinitis. Am J Vet Res 67:1218-1225; Erratum in 67:1627, 2006.
• Haupt JL, Donnelly BP, Nixon AJ. Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explant culture. Am J Vet Res 67:1595-1600, 2006.
• Watts AE, Nixon AJ. Comparison of arthroscopic approaches and accessible anatomic structures during arthroscopy of the caudal pouches of equine femorotibial joints. Vet Surg 35:219-226, 2006.
• Cheetham J, Nixon AJ. Arthroscopic approaches to the palmar aspect of the equine carpus. Vet Surg 35:227-231; Erratum in 35:412, 2006.
• Fealy S, Rodeo SA, MacGillivray JD, Nixon AJ, Adler RS, Warren RF. Biomechanical evaluation of the relation between number of suture anchors and strength of the bone-tendon interface of a goat rotator cuff model. Arthroscopy 22:595-602, 2006.
• MacGillivray JD, Fealy S, Terry MA, Koh JL, Nixon AJ, Warren RF. Biomechanical evaluation of a rotator cuff defect model augmented with a bioresorbable scaffold in goats. J Shoulder Elbow Surg 15:639-644, 2006.
• Strauss EJ, Goodrich LR, Chen CT, Hidaka C, Nixon AJ. Biochemical and biomechanical properties of lesion and adjacent articular cartilage after chondral defect repair in an equine model. Am J Sports Med 33:1647-1653, 2005.
• Semevolos SA, Strassheim ML, Haupt JL, Nixon AJ. Expression patterns of hedgehog signaling peptides in naturally acquired equine osteochondrosis. J Orthop Res 23:1152-1159, 2005.
• Beinlich CP, Nixon AJ. Prevalence and response to surgical treatment of lateral palmar intercarpal ligament avulsion in horses: 37 cases (1990-2001). J Am Vet Med Assoc 226:760-766, 2005.
• van Weeren PR, Nixon AJ. Closing in on the equine joint. Equine Vet J 37:493-494, 2005.
• Nixon AJ, Haupt JL, Frisbie DD Morisset SS, McIlwraith CW, Robbins PD, Evans CH, Ghivizzani S. Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy. Gene Ther 12:177-186, 2005.
• Fortier LA, Nixon AJ. New surgical treatments for osteochondritis dissecans and subchondral bone cysts. Vet Clin North Am Equine Pract 21:673-690, 2005, vii. Review.
• Dahlgren, LA, Nixon AJ. Cloning and expression of equine insulin-like growth factor binding proteins in normal equine tendon. Am J Vet Res 66:300-306, 2005.
• Dahlgren LA, Mohammed HO, Nixon AJ. Temporal expression of growth factors and matrix molecules in healing tendon lesions. J Orthop Res 23:84-92, 2005.
• Haupt JL, Frisbie DD, McIlwraith CW, Robbins PD, Ghivizzani S, Evans CH, Nixon AJ. Dual transduction of insulin-like growth factor-I and interleukin-I receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model. J Orthop Res 23:118-126, 2005.
• Nixon AJ, Schachter BL, Pool RR. Exostoses of the caudal perimeter of the radial physis as a cause of carpal synovial sheath tenosynovitis and lameness in horses: 10 cases (1999-2003). J Am Vet Med Assoc 224:264-270, 2004.
• Nixon AJ, Fortier LA, Goodrich LR, Ducharme NG. Arthroscopic reattachment of osteochondritis dissecans lesions using resorbable polydioxanone pins. Equine Vet J 36:376-383, 2004.
• Trippel SB, Ghivizzani SC, Nixon AJ. Gene-based approaches for the repair of articular cartilage. Gene Ther 11:351-359, 2004.
• Beinlich CP, Nixon AJ. Radiographic and pathologic characterization of lateral palmar intercarpal ligament avulsion fractures in the horse. Vet Radiol Ultrasound 45:532-537, 2004.
• Goodrich LR, Nixon AJ. Treatment options for osteomyelitis. Equine Vet Educ 16:267-280, 2004.
• Hidaka C, Goodrich LR, Chen C-T, Warren RF, Crystal RG, Nixon AJ. Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7. J Orthop Res 21:573-583, 2003.
• Fortier LA, Mohammed HO, Lust G, Nixon AJ. Insulin-like growth factor-I enhances cell-based repair of articular cartilage. J Bone Joint Surg Br 84:276-288, 2002.
• Semevolos S, Brower-Toland BD, Bent S, Nixon AJ. Parathyroid hormone-related peptide and Indian hedgehog expression patterns in naturally acquired equine osteochondrosis. J Orthop Res 20:1290-1297, 2002.

Books

• Nixon AJ. Equine Fracture Repair, Philadelphia, PA, WB Saunders, 1996. Contributing author and editor.
• McIlwraith CW, Nixon AJ, Wright IA, Boening J. Diagnostic and Surgical Arthroscopy in the Horse, 3rd edition, London, UK, Harcourt, 2004. Coauthor.